{
  "target": "T2464",
  "candidate_models": 17683,
  "baseline_weights": {
    "structure": 0.8,
    "confidence": 0.15,
    "model_agreement": 0.05
  },
  "top_100_definition": "The 100 highest-scoring model IDs under the baseline score for this target. Overlap counts model IDs, not unique conformations or correctness.",
  "alternatives": [
    {
      "name": "More confidence",
      "weights": {
        "confidence": 0.25,
        "consensus": 0.05,
        "physics": 0.7
      },
      "spearman_vs_baseline": 0.9933332950390883,
      "original_top100_retained": 64
    },
    {
      "name": "No model agreement",
      "weights": {
        "confidence": 0.18,
        "consensus": 0.0,
        "physics": 0.82
      },
      "spearman_vs_baseline": 0.9944979939932004,
      "original_top100_retained": 47
    },
    {
      "name": "More structural weight",
      "weights": {
        "confidence": 0.1,
        "consensus": 0.0,
        "physics": 0.9
      },
      "spearman_vs_baseline": 0.9931668209907477,
      "original_top100_retained": 49
    },
    {
      "name": "Structural checks only",
      "weights": {
        "confidence": 0.0,
        "consensus": 0.0,
        "physics": 1.0
      },
      "spearman_vs_baseline": 0.9831149281966115,
      "original_top100_retained": 19
    }
  ],
  "massivefold_counts_per_mixed_pool": {
    "AlphaFold 3": 8040,
    "AlphaFold-Multimer": 5025,
    "ESMFold2": 3015,
    "ColabFold": 1005
  },
  "source": "Saved submission score tables and T2464 sensitivity calculations; code at https://github.com/unibio-intelligence/ubistruct-qa"
}